The Addictive Disorders Specialty Section of the Indian Psychiatric Society (IPS) and the IPS Manipur State Branch organized a National CME of Opioid Substitution Therapy (OST) at Imphal. To commemorate the event, a souvenir is released. Titled, “Euphoria”, the souvenir was edited by Shyamanta Das, Athokpam Ranita Devi, and Udayan Majumder, and published by the Society for Mental Health in LAMIC (SoMHiL) with ISBN: 978-81-935934-1-7.

Euphoria consists of one editorial and 15 chapters. The imbalance between clinical work and research activity related to mental health in low and middle income countries (LAMIC) is highlighted, and endeavours to overcome the same are discussed in the Editorial, titled “Thaagatchari” by Shyamanta Das, Athokpam Ranita Devi, and Udayan Majumder.

Guidelines, that authors term as “living document” of OST clinic of a premier institute of the country is presented in Chapter I, titled “Guidelines for ‘recovery oriented opioid substitution therapy’ as currently practiced in PGIMER, Chandigarh” by Abhishek Ghosh, Subodh BN, Debasish Basu, and SK Mattoo.

How the difficulties with naltrexone treatment in opioid use disorder can be overcome by clonidine treatment is discussed in Chapter II, titled “Hypertension: a boon for opioid dependent patient” by Sushil Agarwalla.

Starting with controversies associated with terms like drug and addiction, what can be healthy alternatives to addiction are highlighted in Chapter III, titled “Substance abuse and drug addiction” by Pinaki Chakravarty.

Chapter IV, titled “The addiction gaze” by Pratima Murthy is a narration of how addiction medicine or for that matter psychiatry and medical science as a whole is transforming towards betterment.

From the arrival of the mobile phone to its current status of addiction in some is traced in Chapter V, titled “Mobile phone addiction: an overview” by PJ Chakma.

The law of the land in the form of acts of our country and how over time it evolved to their current versions through various amendments are discussed with merits and demerits as well as comparison of similar in vogue acts in other parts of the globe in Chapter VI, titled “Narcotic Drugs and Psychotropic Substances Act (NDPSA)” by Sanjay Singh and Piyam Sharma.

The menace of the arrival of the recent addictive chemicals is dissected with their nuances in Chapter VII, titled “Legal highs: the new psychoactive substances” by Chayanika Choudhury.

Tracking the timeline from the ancient to the present, this is the journey of the opioids through the world in Chapter VIII, titled “The Afeem Shastra: a brief history of opium” by Amlanjyoti Deb.

Use of substance is approached from a religious point of view in Chapter IX, titled “Hinduism, Lord Shiva and substance abuse” by Udayan Majumder.

A much overlooked phenomenon in our part of the globe about alcohol use in women is evaluated through elaboration of a case vignette in Chapter X, titled “Alcohol and women: how much do we ignore? Let’s explore” by Jita Baruah.

The epidemiological and therapeutic intervention works done in the Northeastern India are focused in relation to substance use disorders in Chapter XI, titled “The global challenge of rising addiction: a Northeast Indian perspective” by Shyamanta Das.

Critical evaluation of the concept of harm reduction is done from medical and social perspectives as well as advantages are presented in Chapter XII, titled “Harm reduction: much misunderstood and even more maligned” by Ashwin Mohan.

How the game of polo began in Manipur and what it means to the Manipuris is focused in Chapter XIII, titled “For the love of a cultural heritage” by Ch Priyoranjan Singh.

The beginning of treatment for opioids use disorder in Manipur led by the Regional Institute of Medical Sciences (RIMS), Imphal to its current status is noted in Chapter XIV, titled “Methadone Maintenance Treatment (MMT) in Manipur: the RIMS experience” by RK Lenin Singh, S Gojendra Singh, Sahana Nagaraj, and N Heramani Singh.

Considering the early onset of opioids use disorder and the challenges associated with the management in this age group is dealt with in Chapter XV, titled “Adolescence and opioid use” by Athokpam Ranita Devi.